382186
Histone Deacetylase 9, His•Tag®, Human Recombinant, S. frugiperda
HDAC9, Human, Recombinant
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
31 May 2012
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Recombinant, human histone deacetylase 9 (HDAC9) consisting of amino acids 604-1066 fused at the C-terminus to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. HDAC9 associates with MEF2 proteins, suppresses their transcriptional activity, and forms a negative-feedback loop in the transcriptional circuitry of muscle differentiation. The active deacetylase is useful in the study of HDAC9 regulation and for inhibitor screening.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 138 mM NaCl, 25 mM Tris-HCl, 10% glycerol, 0.05% TWEEN®-20 detergent, pH 8.0. | ||
| Molar mass | 50700 | ||
| Avoid freeze/thaw | Yes | ||
| Specific activity | ≥0.5 unit/µg protein | ||
| Unit definition | One unit is defined as the amount of enzyme required to deacetylate 1 picomole fluorescent peptide substrate [Arg-His-Lys-Lys(Ac)] per min at 30°C. | ||
| Purity | ≥95% by SDS-PAGE | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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