Intracellular Signaling & Pathway Analysis

• Resource Pages
• Interactive Pathways
• New Products
• Accessory Reagents & Kits
• Relevent Product Spotlights

We offer a wide range of Calbiochem^® and Novagen^® brand kits and reagents for intracellular signaling and pathway analysis. Below are a number of web resources available to you to learn more about these topics and our relevant product offering...

Our product resources provide a great way to browse specific product types and locate all relevant technical information, literature, and graphics.

• Signal Transduction Resource – An overview of inter- and intracellular communication and links to relevant product pages.
• WideScreen™ Multiplex Assays – Quantitate multiple biomarkers and signaling proteins from a single sample using Luminex^® xMAP^® Technology.
• Inhibitor Resource – Accelerate your research with our Inhibitor Resource featuring our new InSolution™ Inhibitors.
• Antibody Resource – Thousands of antibodies for your research in apoptosis, cancer, neuroscience, protein kinases, and much more.
• Kinase Kit Resource – Overview of activity assays and detection kits available for protein kinases.
• Transfection Reagent Resource – Tools for delivering DNA, siRNA, or protein into mammalian cells.
• Guidelines For Choosing a Detergent – Guidelines in selecting a suitable detergent for a variety of applications.
• ProteoExtract™ Sample Preparation – Fast and reproducible extraction of proteins from a wide range of sources including bacteria, yeast, tissue culture cells, and mammalian tissues.
• Protease and Phosphatase Inhibitor Cocktails – Overview and selection guide for protease and phosphatase Inhibitor cocktails.

We offer a variety of Interactive Pathways™ to help you easily find the products you need. Simply click on a target to view relevant products and additional protein information links.

• AKT/Protein Kinase B
• Alzheimer's Disease
• Angiogenesis
• Apoptosis
• Checkpoint Signaling and DNA Repair
• Cytokine Network
• EGFR Signaling
• GSK-3 Signaling
• MAPK Family
• mTOR
• NF-kB
• Nitric Oxide
• p53
• PKA Activation
• Protein Kinase
• Protein Tyrosine Kinases
• Protein Kinase C
• TGF-β Signaling
• Ubiquitin-Proteasome

We introduce new Calbiochem^® and Novagen^® products every month, so make sure to visit our website frequently to view the updated listing of our products that are relevant to your research.

• View all New Products
• Browse Products by Disease Related Pathways
• InhibitorSelect™ Kinase Signaling Pathway Panels
• InhibitorSelect™ Kinase Libraries
• WideScreen™ EpiTag™ Assays – Multiplex quantitation of phosphorylated proteins

These accessory products are designed to help you with your day-to-day lab work, such as Western blotting, transfection, and phosphoprotein extraction and detection.

• 293-Free™ Transfection Reagent – Unique polycationic liposomal formulation designed expressly for transfection of HEK 293 cells grown in suspension culture.
• SignalBoost™ Immunoreaction Enhancer Kit- Designed to enhance the desired signal in assays such as immunoblotting, dot blotting, and ELISA.
• RapidStep™ ECL Reagent – A one-step chemiluminescent substrate reagent for detection of horseradish peroxidase (HRP) labeled antibodies on immunoblots.
• FluorPreserve™ Reagent – Excellent mounting media for fluorescent staining procedures.
• Phosphoprotein Extraction & Detection Products – Extraction reagents, antibodies to phosphoserine, phosphotyrosine, phosphothreonine, and related reagents.

Product Spotlights are a good way for you to obtain a quick overview of topics of interest and to view our relevant product offering.

• PhosphoDetect™ Antibodies & ELISA Kits – Over 200 phospho-specific antibodies directed to targets in the areas of neurobiology, apoptosis, cell cycle regulation, transcription factors, receptor tyrosine kinases, Ser/Thr Kinases, and more.
• Tools for Proteasome Research – Ubiquitin-proteasome pathway plays an important role in cell cycle, signal transduction, and in maintaining the structural integrity of the protein. View ubiquitin-proteasome pathway related antibodies, inhibitors, enzymes, and kits.
• Tools for Mitochondrial Metabolism – View antibodies and kits for the study of mitochondrial metabolism.
• K-LISA™ mTOR Activity Kits – Overview of kits suitable for measuring the kinase activity of purified or partially purified preparations of mTOR or mTOR that has been immunoprecipitated from crude cell lysates.