N-a-Fmoc protected amino acids attached to NovaSyn® TGT resin


NovaSyn® TGT resins consist of NovaSyn® TG resin derivatized with Bayer's extremely acid-sensitive 4-carboxytrityl linker. The 90 µm beads have a narrow size distribution, excellent pressure stability and swelling properties, and high diffusion rates, making them ideally suited for both batch or continuous flow peptide synthesis. Cleavage can be effected by treatment with AcOH/TFE/DCM (2:2:6), 0.5% TFA in DCM, or 30% HFIP in DCM, to yield protected peptide acid fragments without any loss of sensitive side-chain protecting groups. Because enantiomerization can not occur during attachment of the first residue to TGT resin, peptides containing C-terminal Cys and His residues can be produced free from contamination by diastereomeric side-products. This support is also particularly suited to the synthesis of prolyl peptides as the bulk of the trityl handle prohibits diketopiperazine formation.

Productos en esta categoría:
Número de producto Productos
856125 Fmoc-Ala-NovaSyn® TGT  Novabiochem®
856052 Fmoc-Arg(Pbf)-NovaSyn® TGT  Novabiochem®
856126 Fmoc-Asn(Trt)-NovaSyn® TGT  Novabiochem®
856127 Fmoc-Asp(OtBu)-NovaSyn® TGT  Novabiochem®
856044 Fmoc-Cys(Trt)-NovaSyn® TGT  Novabiochem®
856128 Fmoc-Gln(Trt)-NovaSyn® TGT  Novabiochem®
856129 Fmoc-Glu(OtBu)-NovaSyn® TGT  Novabiochem®
856045 Fmoc-Gly-NovaSyn® TGT  Novabiochem®
856046 Fmoc-His(Trt)-NovaSyn® TGT  Novabiochem®
856130 Fmoc-Ile-NovaSyn TGT  Novabiochem®
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