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01 June 2012
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N-terminal active peptide fragment of the native hormone that functions as a regulatory factor in the homeostatic control of Ca2+ and phosphate metabolism. Regulates Ca2+ and phosphate flux across cellular membranes in bone and kidney, resulting in increased serum Ca2+ levels. Increases the activity of osteoblasts and osteoclasts. Increases tubular reabsorption of Ca2+ and stimulates renal hydroxylation of 25-(OH)-Vitamin D3 to 1,25-(OH)2-Vitamin D3. Increases the production of inhibitory IGF binding protein 4 in bone cells.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH | ||
| Form | White to off-white lyophilized solid | ||
| Formulation | Supplied as an acetate salt. | ||
| Molar mass | 4117.8 | ||
| Protect from Moisture | Yes | ||
| Purity | ≥95% by HPLC | ||
| Sold on the basis of peptide content | Yes | ||
| Solubility | 5% Acetic Acid | ||
| Chemical formula | C181H291N55O51S2 | ||
| CAS number | 52232-67-4 | ||
| Merck USA index | 14, 7034 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
||
