616402
TACE Substrate II, Fluorogenic
TNF-α Convertase Enzyme Substrate, Fluorogenic, MCA-PLAQAV(Dpa)RSSSR-NH2, ADAM-17 Substrate II, Fluorogenic
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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A fluorogenic peptide substrate for TACE (Km = ~ 19 µM). Substrate cleavage occurs at the Ala-Val bond. Useful for screening TACE Inhibitors.
| Product information | |||
|---|---|---|---|
| Peptide Sequence | MCA-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2[Dpa = N-3-(2,4-Dinitrophenyl)-L-2,3-diaminopropionyl] | ||
| Form | Liquid | ||
| Formulation | A 4 mM (7.5 mg/ml) solution in DMSO. | ||
| Molar mass | 1638.7 | ||
| Protect from Light | Yes | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥90% by HPLC | ||
| Chemical formula | C69H103N23O24 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Standard Handling |
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