612400
Tissue Transglutaminase, His•Tag®, Human, Recombinant, S. frugiperda
rh-tTG, TGase
For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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Full-length, recombinant, human tissue transglutaminase fused to a His•Tag® sequence and expressed in s. frugiperda insect cells. Suitable as a control for ELISA or Western blots. Tissue transglutaminase is a calcium-activated enzyme, which forms cross-links between glutamine and lysine side-chains of polypeptides. TGase-mediated protein crosslinking has been implicated in a variety of natural processes ranging from the stabilization of fibrin clots to production of the epidermal cell envelope and the fluid barrier of the skin. TGases are also involved in both function and dysfunction of the central and peripheral nervous systems. More recently, TGases have been implicated in the onset of Huntington’s Disease (HD) as well as Celiac Disease (CD).
Suitable for use as a standard in ELISA or immunoblots.
| Product information | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 20 mM Tris-HCl, 1 mM EDTA, 20% glycerol, pH 8.1-8.5. | ||
| Molar mass | 85000 | ||
| Avoid freeze/thaw | Yes | ||
| Purity | ≥90% by SDS-PAGE | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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