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01 June 2012
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A nucleoside antibiotic that inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. Also inhibits thrombin-induced Ca2+ mobilization in cells.
M.W. 840.0 (n = 10).
| Product information | |||
|---|---|---|---|
| Form | White to off-white solid | ||
| Primary Target | N-linked glycosylation | ||
| Secondary target | thrombin-induced Ca2+ mobilization in cells | ||
| Molar mass | 840.9 | ||
| Purity | ≥95% by HPLC (A+B+C+D) | ||
| Reconstitution | Aqueous solutions can be prepared from stock solutions in DMSO by diluting with H2O at pH 8.0 to 10.0 or with appropriate buffers at pH >7.0 (preferably >8.0). | ||
| Solubility | DMF, DMSO, or Pyridine | ||
| Chemical formula | C39H60N4O16 | ||
| RTECS | YO7980200 | ||
| CAS number | 11089-65-9 | ||
| Merck USA index | 14, 9819 | ||
| Store and ship information | |||
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Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. |
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| Storage | +15°C to +30°C | ||
| Ship |
Ambient Temperature Only
Highly Toxic & Carcinogenic / Teratogenic |
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| Safety information | |||
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| S Phrase |
S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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| R Phrase |
R: 26/27/28-60-61 Very toxic by inhalation, in contact with skin and if swallowed. May impair fertility. May cause harm to the unborn child. |
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