For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
01 June 2012
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This product has been discontinued.
Please refer to our complete listing of antimicrobial agents for possible alternatives. Please read the alternative product documentation carefully and contact technical service if you need additional information.
A cell-permeable naphthalimide compound that inhibits virulence regulation in Vibrio cholerae. Shown to target the transcriptional regulator ToxT, block its dimerization, and prevent the expression of cholera toxin and the toxin coregulated pilus (TCP) with minimal bacterial toxicity. Effectively protects infant mice against TCP-dependent V. cholerae intestinal colonization in vivo. Displays little toxicity towards mammalian cells (up to 2mM for Hep2 cells).
| Product information | |||
|---|---|---|---|
| Form | Pale yellow solid | ||
| Molar mass | 283.3 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥97% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C16H13NO4 | ||
| CAS number | 88909-96-0 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | +2°C to +8°C | ||
| Ship |
Ambient Temperature Only
Harmful |
||
