For general questions please contact our Customer Service:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
04 June 2012
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This product has been replaced by WideScreen® BeadPlex™ Human Cancer Panel 1 (Cat. No. BPHCP001-6)
The WideScreen® Human Cancer Panel 1 (Tumor Markers) is a pre-mixed multiplex bead kit of quantitative antibody-based assays for simultaneous detection of six tumor-associated human proteins found in biological fluids: AFP (a-fetoprotein), CA 125, CA15-3, CA 19-9, CEA (carcinoembryonic antigen), and prolactin. The kit includes all the reagents, controls, and buffers needed to analyze the above proteins in serum, plasma, and tissue culture supernatants using the Luminex® xMAP® System.
The WideScreen® Human Cancer Panel 1 uses the same reagents and technologies developed by Rules Based Medicine for the use in their industry-leading biomarker testing service along with the expertise of Novagen in commercializing and supporting high value products. Accordingly, the kits are supplied with the highest quality and relevant validation data, ensuring that each assay kit meets the stringent quality and performance required in today’s demanding research environment.
Performance Characteristics |
Species |
Human, other species not tested |
|
Sample Size |
6 µl |
|
Sample Types
|
Serum, plasma, tissue culture supernatants
|
|
| Linearity % recovery across dilutions |
Dilution 1:10 1:20 1:40 |
Range 91%-111% 92%-103% 93%-111% |
Intra-assay CV |
3%-15% |
|
| Inter-assay CV | 7%-24% |
|
Cross-reactivity
|
Negligible
|
|
Matrix Interference |
Hemoglobin (5mg/ml) 72% to 100% Bilirubin (0.2 mg/ml) 81% to 92% Triglycerides (5mg/ml) 101% to 126% |
|
Analyte |
Standard Range |
Assay LDD |
Average Recovery from Serum |
Average Recovery from EDTA Plasma |
Normal Range* |
AFP |
0.15-333 ng/ml |
0.15 ng/ml |
92% |
101% |
<20 ng/ml |
CA 125 |
0.55-1200 U/ml |
0.30 U/ml |
144% |
131% |
<35 U/ml |
CA 15-3 |
0.18-392 U/ml |
0.18 U/ml |
96% |
108% |
<25 U/ml |
CA 19-9 |
0.15-320 U/ml |
0.15 U/ml |
87% |
98% |
<37 U/ml |
CEA |
0.017-37 ng/ml |
0.017 ng/ml |
76% |
84% |
<5 ng/ml |
Prolactin |
0.017-38 ng/ml |
0.017 ng/ml |
72% |
74% |
<29 ng/ml** |
| *Normal range data from American Cancer Society website, www.cancer.org and other sources. |
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| Components |
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| Store and ship information | |||
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| Storage | +2°C to +8°C | ||
| Ship |
Blue Ice Only
Standard Handling |
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| Safety information | |||
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| S Phrase |
S: 26-36/37/39-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
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