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Active pharmaceutical ingredients (APIs)

Top quality and exceptional service: Active pharmaceutical ingredients (APIs) from Merck Millipore

Top quality and service: APIs from Merck

The one thing that counts in the production of active pharmaceutical ingredients is quality. As a global pharma company with extensive experience in drug research and production, Merck Millipore has the resources and the competences to always deliver highest quality with exceptional service to boot. With APIs from Merck Millipore, you are on the safe side!

Your benefits:
  • Experienced, reliable partner for the pharma industry
  • Top-quality APIs
  • Higher bioavailability for your APIs
  • Competent support – from development to registration

First-class products and service

With more than 400 pharmaceutical raw materials on offer worldwide, we are a reliable partner for pharmaceutical manufacturers for many years. Our API-related portfolio comprises folates and drug delivery compounds as well as our EMPROVE® api product family. Moreover, we provide comprehensive support for all stages of your API development and production: from process development and optimization up to regulatory affairs. APIs from Merck Millipore are produced in the highest quality and in accordance with current Good Manufacturing Practice (cGMP) guidelines, and they are subject to strict quality assurance procedures.

High-purity folates – exclusively from Merck Millipore

Decades of experience in the manufacture of active pharmaceutical ingredients speak for themselves:
As early as 1965, a swiss subsidiary of Merck KGaA started the production of the high-purity folate Calcium Folinate (Leucovorin Calcium). Merck Millipore was also the first one able to produce Calcium Levofolinate (Levoleucovorin Calcium) in commercial quantities. In 2002, Merck Millipore exclusively launched its patented L-methylfolate Metafolin® that can be used by the body directly without prior activation. Folates play a key role in central metabolic processes, e. g. for cell division or cell repair.

Drug Delivery Compounds – for better bioavailability

For pharmaceutical manufacturers, Merck Millipore provides customized drug delivery compounds that optimize the bioavailability of active pharmaceutical ingredients in the body. While DDC are not active ingredients themselves, they enhance their potency and are produced under comparable conditions. Our products range from PEGs (polyethylene glycols) to lipids (to form liposomes) to PEG-lipids for parenteral application. In addition to our cGMP-quality products, we offer professional support in process and analytical development or manufacture your proprietary products – also strictly according to cGMP guidelines.

EMPROVE® api – for faster time to market

Under the brand name EMPROVE® api, Merck Millipore offers high-quality raw materials for use as active pharmaceutical ingredients. Manufactured under cGMP conditions, EMPROVE® api products meet the highest quality and safety standards with regard to current and future regulatory requirements. Comprehensive and ready-to-use documentation facilitates your approval process. In a nutshell, with EMPROVE® api you achieve maximal product safety and save time and money in drug registration and market launch.

Supporting your new ideas

You are developing a new active pharmaceutical ingredient or would like to use a particular excipient as API? Merck Millipore is your competent partner for the realization of your new ideas – with highly specialized services, key product know-how, and technical expertise. We provide just the product amounts you need for your respective development stage and support you with regard to the optimization and provision of regulated intermediates and APIs in the required scale.

For more information, please contact us.

© Merck KGaA, Darmstadt, Germany, 2014


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