Drug Delivery Compounds
Many pharmaceutical companies are looking for ways to optimize the bioavailability of their newly developed active pharmaceutical ingredients (APIs) in the body. Mainly, the efficacy of biopharmaceuticals such as enzymes, peptides and nucleotides benefits from the combination with drug delivery compounds.
Drug delivery compounds consist of a broad spectrum of molecules that are chemically bound to an API or are part of the drug vehicle. The most important drug delivery technologies are PEGylation, incorporation into liposomes, biopolymers as well as combinations thereof, for example PEGylated liposomes.
Merck offers customized drug delivery compounds such as PEGs (polyethylene glycols), lipids (to form liposomes) and PEG-lipids for parenteral application. Our service ranges from process and analytical development to cGMP production. Benefit from our highly specialized services, technical expertise and key product know-how for your business success.
Advantages at a glance:
| PEGylation Technology | Liposome Technology |
| - Increased bioavailability - Optimized pharmacokinetics - Decreased immunogenicity - Decreased frequency of administration |
- Increased solubility and bioavailability - Drug targeting and less side effects - Sustained release |
If you would like further information, see also www.eprovadrugdelivery.com or please contact us.
We would be delighted to hear from you and we look forward to collaborating with you!
