SeQuant™ ZIC^®-HILIC HPLC Columns

Your ideal choice for separation of polar and hydrophilic compounds is SeQuant™ ZIC^®-HILIC and ZIC^®-pHILIC HPLC columns. Reproductible retention, of all types of compounds that have proved difficult to separate on reversed-phase HPLC columns, is ensured by the high-performance, zwitterionic stationary phase in these columns. Straightforward separation of compounds such as acids and bases,link to application pges anions and cations, carbohydrates, metabolites, metal complexes, amino acids, peptides, protein digests, can therefore be achieved. The US FDA has recommended methods for determination of melamine and cyanuric acid in food products based on the ZIC-HILIC column. Enhanced LC/MS sensitivity is an additional benefit of using these columns.

The silica-based ZIC^®-HILIC is suitable for most HILIC applications. ZIC^®-pHILIC is polymer-based, has a wider pH stability range, making it the choice for extra difficult separations demanding more extreme eluent conditions. Columns are available in a wide range of formats from capillary to semi-preparative dimensions, and with several different particles sizes and pore sizes.