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Buffers from Merck Millipore

For the sake of your protein

Buffer quality is vital for the success of biopharmaceutical processes because they are indispensable in nearly every production step. Merck Millipore offers you a wide range of buffer materials to cover all commonly used buffering systems, such as phosphates, acetates or organic buffers like TRIS, HEPES or MES.

In upstream processes, buffers optimize pH and other process parameters in order to obtain the desired product characteristics. In downstream, they help maintaining defined purification conditions to stabilize your valuable proteins while protecting them from unwanted contamination.

 

Benefits
  • All manufactured to GMP*
  • Multicompendial (in case applicable)
  • Low bioburden and endotoxin levels
  • Low UV-absorbance of aqueous solutions

Full range of buffers – for minimized risk

In order to ensure reproducible processes, Merck Millipore uses only high-purity raw material of defined specifications. Our manufacturing processes have been designed to minimize microbiological contamination and endotoxin concentrations. In addition, most buffers are specified to non-detectable enzymatic activities of DNases, RNases, or proteases. This is what makes these buffers particularly suitable for biochromatography. Qualification kits with samples from three batches are available on request.

EMPROVE® bio – comprehensive regulatory documentation

Most of our buffer products bear the EMPROVE® bio trademark. EMPROVE® products are conceived to make your work even faster and more cost-efficient: they come with comprehensive regulatory documentation that contributes considerably to the quality part of your registration dossier.

 

Phosphates Acetates Citrates TRIS + organic pH adjustment

137039

KH2PO4

137000

HOAc 100%

137002

Citric acid

108307

TRIS High Purity

110165

HCI 1N

137010

K2HPO4

137047

HOAc 30%

137003

Citric acid-H2O

108386

TRIS

137031

NaOH 1N

137036

Na2HPO4

137046

NaOAc

137042

Na-citrate

108219

TRIS-HCI

137035

HOAc 1N

137017

NaCl

137012

NaOAc-3H2O

 

137017

NaCl

 

137018

NaH2PO4

 

 

110110

HEPES

 

 

   

137074

MES-Na

 

We also offer ready-to-use buffer solutions in disposable bags. For more information please click here.

For more information please contact us.

 

 * based on IPEC - PQG GMP Guide for pharmaceutical excipients 2006.

© Merck KGaA, Darmstadt, Germany, 2014


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