407601
Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor
N-(2-Morpholinylethyl)-2-(3-nitrobenzoylamido)-benzimidazole, IRAK-1/4 Inhibitor
หากท่านมีคำถาม กรุณาติดต่อเจ้าหน้าที่ลูกค้าสัมพันธ์ :
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Phone: +49 6151 72-0
Fax: +49 6151 72 2000
24 พฤษภาคม 2556
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A cell-permeable benzimidazole compound that acts as a potent and selective inhibitor of interleukin-1 receptor-associated kinases (IC50 = 300 nM and 200 nM for IRAK-1 and -4). Shown to exhibit little activity against a panel of 27 other kinases (IC50 >10 µM), including lck and src. Also available as a 25 mM solution in DMSO (Cat. No. 407602).
| Product information | |||
|---|---|---|---|
| Form | Yellow crystalline solid | ||
| Molar mass | 395.4 | ||
| Protect from Light | Yes | ||
| Packaged under inert gas | Yes | ||
| Purity | ≥98% by HPLC | ||
| Solubility | DMSO | ||
| Chemical formula | C20H21N5O4 | ||
| CAS number | 509093-47-4 | ||
| Store and ship information | |||
|---|---|---|---|
| Storage | -20°C | ||
| Ship |
Ambient Temperature Only
Harmful |
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| Safety information | |||
|---|---|---|---|
| S Phrase |
S: 36 Wear suitable protective clothing. |
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| R Phrase |
R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. |
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