Genel sorular için lütfen Müşteri Hizmetleri ile iletişime giçin:
Merck KGaA
Frankfurter Str. 250
64293 Darmstadt
Germany
Telefon: +49 6151 72-0
Faks: +49 6151 72 2000
04 Haziran 2012
yükleniyor
Native, DPP IV purified from porcine kidney (renal brush border of the proximal tubule). A serine exopeptidase dimer composed of two identical subunits of 110-130 kDa. Cleaves Xaa-Pro dipeptides from the N-terminus of oligo and polypeptides. DPPIV is involved in many cellular processes such as activation of cytokines, differentiation, T cell activation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. MW: ~210000-260000 (unreduced).
| Ürün bilgisi | |||
|---|---|---|---|
| Form | Liquid | ||
| Formulation | In 20 mM Tris-HCl, 5 mM CaCl2, 1 µM ZnCl2, 0.05% NaN3, pH 8.0. | ||
| Avoid freeze/thaw | Evet | ||
| Specific activity | ≥35 units/mg protein | ||
| Unit definition | One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmole 7-(Gly-Pro)-amino-4-methylcoumarinamide per min at 37°C, pH 8.5. | ||
| Purity | ≥90% by SDS-PAGE | ||
| EC number | 3.4.14.5 | ||
| Depolama ve yükleme bilgisi | |||
|---|---|---|---|
| Storage | ≤ -70°C | ||
| Ship |
Dry Ice Only
Standard Handling |
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