On-Demand Webinar

Preparative HPLC Part II: Process Development and Troubleshooting
– A "how to" guide.

Duration: 1 Hour
Speaker: Dr. Michael Schulte, Purification R&D, Cation Exchange and New Surfaces, Merck

Abstract: Shifting peaks? Insufficient resolution? Low purity and yield? – When facing troubles in preparative HPLC a variety of different effects can be the underlying reason. In this webinar, Michael Schulte will provide you with key guidelines from his 20+ years of experience in preparative HPLC to effectively apply troubleshooting and hence to solve your HPLC challenges.

Join us for this part II webinar as we will focus on:
  • Stationary phase conditioning and cleaning in normal as well as reversed phase mode
  • Challenges arising from low feed solubilities
  • Design and maintenance issues related to preparative columns and systems

and learn how:

  • Thin Layer Chromatography can show you what´s typically not visible
  • You can virtually elongate your column
  • A slight shift in pH can massively influence the separation
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