AP5Z1
adaptor-related protein complex 5, zeta 1 subunit
Synonyms:
KIAA0415, SPG48, zeta
Species:
Human AP5Z1 (9907), Mouse Ap5z1 (231855), Rat Ap5z1 (641386), naked mole-rat Ap5z1 (101724730), domestic cat AP5Z1 (101094558), dog AP5Z1 (609375), domestic guinea pig Ap5z1 (100731381), sheep AP5Z1 (101110022), chicken AP5Z1 (416478)
UniProtKB ID:
Gene ID:
- Human(9907) Summary: This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]
- Mouse(231855) adaptor-related protein complex 5, zeta 1 subunit
- Rat(641386) adaptor-related protein complex 5, zeta 1 subunit
- naked mole-rat(101724730) adaptor-related protein complex 5, zeta 1 subunit
- domestic cat(101094558) adaptor-related protein complex 5, zeta 1 subunit
- dog(609375) adaptor-related protein complex 5, zeta 1 subunit
- domestic guinea pig(100731381) adaptor-related protein complex 5, zeta 1 subunit
- sheep(101110022) adaptor-related protein complex 5, zeta 1 subunit
- chicken(416478) adaptor-related protein complex 5, zeta 1 subunit
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