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Merck

PROZ

protein Z, vitamin K-dependent plasma glycoprotein

Synonyms:
PZ
Species:
UniProtKB ID:
Gene ID:
  • Human(8858) Summary: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Mouse(66901) protein Z, vitamin K-dependent plasma glycoprotein
  • Rat(306608) protein Z, vitamin K-dependent plasma glycoprotein
  • naked mole-rat(101704499) protein Z, vitamin K-dependent plasma glycoprotein
  • chicken(418746) protein Z, vitamin K-dependent plasma glycoprotein
  • domestic guinea pig(100714435) protein Z, vitamin K-dependent plasma glycoprotein
  • cow(617946) protein Z, vitamin K-dependent plasma glycoprotein

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PROZ antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PROZ antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PROZ antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Proz,
Species
mouse
MISSION® esiRNA, targeting human PROZ,
Species
human