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444190 MAP Kinase Inhibitor Set II - Calbiochem


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      OverviewContains 5 mg of PD 98059 (Cat. No. 513000), 1 mg each of SB 203580 (Cat. No. 559389), and U0126 (Cat. No. 662005), and 1 mg of Proteasome Inhibitor I (Cat. No. 539160), which serves as a negative control.
      Catalogue Number444190
      Brand Family Calbiochem®
      Product Information
      Quality LevelMQ100
      Biological Information
      Primary TargetMAP kinase
      Primary Target IC<sub>50</sub>2 µM
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Global Trade Item Number
      Catalogue Number GTIN
      444190-1SET 04055977205541


      MAP Kinase Inhibitor Set II - Calbiochem SDS


      Safety Data Sheet (SDS) 

      MAP Kinase Inhibitor Set II - Calbiochem Certificates of Analysis

      TitleLot Number
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-August-2020 JSW
      DescriptionThe Mitogen-activated protein kinases (MAP Kinases) are a group of protein serine/threonine kinases that are activated in response to a variety of extracellular stimuli and mediate signal transduction from the cell surface to the nucleus. MAP kinases, in combination with several other signaling pathways can differentially alter phosphorylation status of the transcription factors that is unique to a given signal from outside the cell. A controlled regulation of these cascades is involved in cell proliferation and differentiation, whereas an unregulated activation of these MAP kinases can result in oncogenesis. Three major types of MAP kinase cascades have been reported in mammalian cells that respond synergistically to different upstream signals. They are ERK1/ERK2 MAP kinases, the JNK/SAPK (c-Jun kinase/stress activated protein kinase), and the p38 kinase.

      The Calbiochem® MAP Kinase Inhibitor Set II contains 4 inhibitors with different MAP Kinase specificities for your convenience.
      Intert gas (Yes/No) Packaged under inert gas
      Storage Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze
      Toxicity Standard Handling