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Merck

475814

Microcystin-LF, Microcystis aeruginosa - Calbiochem

Synonym(s):

Microcystin-LF, Microcystis aeruginosa - Calbiochem, MCYST-LF

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About This Item

Empirical Formula (Hill Notation):
C52H71N7O12
Molecular Weight:
986.16
UNSPSC Code:
12352200

Key Documents

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color

colorless

assay

≥95% (HPLC)

form

film

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

methanol: 2 mg/mL
DMSO: 2.5 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Biochem/physiol Actions

Cell permeable: yes
Primary Target
Protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A)
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Highly Toxic (H)

General description

This product has been discontinued.



Analog of Microcystin-LR (Cat. No. 475815) with Phe substituted in place of Arg. Believed to be more cell-permeable than other microcystins, making it useful for biochemical studies in intact cells.

Analog of Microcystin-LR (Cat. No 475815) with Phe group substituted in place of Arg. Believed to be more cell-permeable than other microcystins, making it useful for biochemical studies in intact cells.

Legal Information

Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Lawton, L.A., et al. 1995. Nat. Toxins 3, 50.
Lawton, L.A., et al. 1994. Analyst. 119, 1525.

Packaging

yes

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Certificates of Analysis (COA)

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L A Lawton et al.
The Analyst, 119(7), 1525-1530 (1994-07-01)
Increasing concern over the presence of microcystins (cyanobacterial/blue-green algal hepatotoxins) in water supplies has emphasized the need for a suitable analytical method. As many microcystins are known to exist, a method was developed that permits the determination of numerous variants
L A Lawton et al.
Natural toxins, 3(1), 50-57 (1995-01-01)
Six microcystins were identified in a laboratory culture of the cyanobacterium (blue-green alga) Microcystis aeruginosa PCC 7813 using high-performance liquid chromatography coupled with diode array detection (HPLC-DAD) and mass spectrometry (LC-MS). The toxins were purified and further characterized by amino

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