- Rhodium acetate/base-catalyzed N-silylation of indole derivatives with hydrosilanes.
Rhodium acetate/base-catalyzed N-silylation of indole derivatives with hydrosilanes.
Chemical communications (Cambridge, England) (2012-08-10)
Shintaro Itagaki, Keigo Kamata, Kazuya Yamaguchi, Noritaka Mizuno
PMID22875054
ABSTRACT
In the presence of Rh(2)(OAc)(4) (OAc = acetate) and TBA(2)WO(4) (TBA = tetra-n-butylammonium), the N-silylation of indole derivatives with hydrosilanes efficiently proceeded to give the corresponding N-silylated indoles in high yields. Pyrrole and carbazole were also N-silylated with the combined catalysts.
MATERIALS
Product Number
Brand
Product Description
Supelco
Tetrabutylammonium bisulfate solution, suitable for ion pair chromatography, LiChropur™, concentrate, ampule