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A major human histone gene cluster on the long arm of chromosome 1.

Science (New York, N.Y.) (1984-11-16)
L Green, R Van Antwerpen, J Stein, G Stein, P Tripputi, B Emanuel, J Selden, C Croce
ABSTRACT

A human histone gene cluster was assigned to chromosome 1 by Southern blot analysis of DNA's from a series of mouse-human somatic cell hybrids with 32P-labeled cloned human H4 and H3 histone DNA as probes. Localization of this histone gene cluster on the long arm of chromosome 1 was confirmed by in situ hybridization of this DNA probe to metaphase chromosomes.