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A smart nanofiber web that captures and releases cells.

Angewandte Chemie (International ed. in English) (2012-09-20)
Young-Jin Kim, Mitsuhiro Ebara, Takao Aoyagi
ABSTRACT

Caught in a web: Photo-cross-linkable temperature-responsive polymer-based nanofiber webs have been synthesized that have the ability to capture, encapsulate, and release cells by dynamically transforming the fibrous structure into hydrogel-like structures by wrapping, swelling, and deswelling processes in response to external temperature changes (see picture).

MATERIALS
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Sigma-Aldrich
N-Isopropylacrylamide, ≥99%