RABBIT ANTI-CNG2 (Cyclic Nucleotide-Gated Cation Channel 2, OCNC1, Cnga2) AFFINITY PURIFIED, POLYCLONAL ANTIBODY
- Document Type:
- Data Sheet
Nucleotide-gated
49 Results
Advanced Search
Showing
Narrow Your Results Use the filters below to refine your search
Document Type
-
-
RABBIT ANTI-CYCLIC NUCLEOTIDE-GATED CHANNEL 1 (CNG1) AFFINITY PURIFIED POLYCLONAL ANTIBODY -
- Document Type:
- Certificate of Analysis
- Product Catalog Number:
- AB3582P
- Product Catalog Name:
- Anti-Cyclic Nucleotide-Gated Channel 1 Antibody, CT
-
Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice.
- In the olfactory bulb, input from olfactory receptor neurons is processed by neuronal networks before it is relayed to higher brain regions. In many neurons, hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels generate and control oscillations of the membrane potential. Oscillations also appear crucial for information processing in the olfactory bulb. Four channel isoforms exist (HCN1-HCN4) that can form homo- or heteromers. Here, we describe the expression pattern of HCN isoforms in the olfactory bulb of mice by using a novel and comprehensive set of antibodies against all four isoforms. HCN isoforms are abundantly expressed in the olfactory bulb. HCN channels can be detected in most cell populations identified by commonly used marker antibodies. The combination of staining with marker and HCN antibodies has revealed at least 17 different staining patterns in juxtaglomerular cells. Furthermore, HCN isoforms give rise to an unexpected wealth of co-expression patterns but are rarely expressed in the same combination and at the same level in two given cell populations. Therefore, heteromeric HCN channels may exist in several cell populations in vivo. Our results suggest that HCN channels play an important role in olfactory information processing. The staining patterns are consistent with the possibility that both homomeric and heteromeric HCN channels are involved in oscillations of the membrane potential of juxtaglomerular cells.
- Document Type:
- Reference
- Product Catalog Number:
- AB1550
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2453133
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2453133
- Product Catalog Number:
- AB5808-200UL
- Product Catalog Name:
- Anti-HCN4 Antibody
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2181247
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2181247
- Product Catalog Number:
- AB5808-200UL
- Product Catalog Name:
- Anti-HCN4 Antibody
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2105117
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2105117
- Product Catalog Number:
- AB5808-200UL
- Product Catalog Name:
- Anti-HCN4 Antibody
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2042715
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2042715
- Product Catalog Number:
- AB5808-200UL
- Product Catalog Name:
- Anti-HCN4 Antibody
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2297163
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2297163
- Product Catalog Number:
- AB5808-50UL
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2143447
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2143447
- Product Catalog Number:
- AB5808-50UL
-
RABBIT ANTI-HCN4 (Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 4) AFFINITY PURIFIED, POLYCLONAL ANTIBODY - 2001220
- Document Type:
- Certificate of Analysis
- Lot Number:
- 2001220
- Product Catalog Number:
- AB5808-200UL
- Product Catalog Name:
- Anti-HCN4 Antibody