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AB9415 Anti-Cannabinoid Receptor 1 Antibody

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AB9415
50 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, Mk, RICC, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9415
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Cannabinoid Receptor 1 Antibody
      Alternate Names
      • CB1
      References
      Product Information
      FormatAffinity Purified
      HS Code3002 15 90
      PresentationAffinity purified immunoglobulin. Liquid in PBS, with less than 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Cannabinoid Receptor 1 Antibody detects level of Cannabinoid Receptor 1 & has been published & validated for use in IC, IH(P).
      Key Applications
      • Immunocytochemistry
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on formalin fixed paraffin embedded tissue sections.

      Immunocytochemistry on acetone fixed cells.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the 3rd cytoplasmic domain of human Cannabinoid Receptor 1. The immunogen sequence has 100% homology with mouse.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Cannabinoid Receptor 1 [CB1].
      Species Reactivity
      • Human
      • Monkey
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a protein that is one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the family of guanine-nucleotide-binding protein (G-protein) coupled receptors which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Two transcript variants encoding different isoforms have been described for this gene.
      Gene Symbol
      • CNR1
      • CNR
      • CB1K5
      • CANN6
      • CB1A
      • CB-R
      • CB1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P21554 # Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Isoform 2 and isoform 3 have altered ligand binding.
      SIZE: 472 amino acids; 52858 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Widely expressed.
      SIMILARITY: SwissProt: P21554 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9415 04053252280214

      Documentation

      Anti-Cannabinoid Receptor 1 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Cannabinoid Receptor 1 Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2152957 2152957
      RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2410978 2410978
      RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2143906 2143906
      RABBIT ANTI- CANNABINOID RECEPTOR 1 - 3255327 3255327
      RABBIT ANTI- CANNABINOID RECEPTOR 1 - 4187070 4187070
      RABBIT ANTI- CANNABINOID RECEPTOR 1 -2638910 2638910
      RABBIT ANTI- CANNABINOID RECEPTOR 1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2925266

      Data Sheet

      Title
      RABBIT ANTI- CANNABINOID RECEPTOR 1

      Related Products & Applications

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      Catalogue Number Description  
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies