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ABT338 Anti-EBI3 Antibody

Detect IL-27 using this rabbit polyclonal antibody, Anti-EBI3 Antibody validated for use in western blotting, IHC & Immunofluorescence.

Anti-EBI3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytokines & Cytokine Receptors Gene Symbol: EBI3, IL27B UniProt Number: Q14213
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ABT338
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT338
      DescriptionAnti-EBI3 Antibody
      Alternate Names
      • Interleukin-27 subunit beta
      • IL-27 subunit beta
      • IL-27B
      • Epstein-Barr virus-induced gene 3 protein
      • EBV-induced gene 3 protein
      Background InformationEpstein-Barr virus-induced gene 3 protein (EBI3), also known as Interleukin-27 subunit beta (IL27B), is a member of the type I cytokine receptor family (Type 3 subfamily) that is composed of two subunits: interleukin-27 (IL-27) and IL-35. EBI3 regulates T-helper cell development, stimulates cytotoxic T-cell activity, suppresses T-cell proliferation, and induces isotype switching in B-cells. EBI3 also plays an important role in its antitumor activity as well as its antiangiogenic activity.
      References
      Product Information
      FormatAffinity Purified
      Control
      • K562 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect IL-27 using this rabbit polyclonal antibody, Anti-EBI3 Antibody validated for use in western blotting, IHC & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected EBI3 in human spleen tissue.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected EBI3 in human spleen cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human EBI3.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of EBI3.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • EBI3
      • IL27B
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~37 kDa observed. Uncharacterized bands may appear in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting/Peptide Inhibition Assay in K562 cell lysate.

      Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected EBI3 in 15 µg of K562 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT338 04053252905506