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MABS460 Anti-FGF23 Antibody, clone 278-2

Anti-FGF23 Antibody, clone 278-2 is a mouse monoclonal antibody & validated for use in western blotting.

Anti-FGF23 Antibody, clone 278-2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: FGF23, HYPF UniProt Number: Q9GZV9
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MABS460
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, FCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS460
      DescriptionAnti-FGF23 Antibody, clone 278-2
      Alternate Names
      • Fibroblast growth factor 23
      • FGF-23
      • Phosphatonin
      • Tumor-derived hypophosphatemia-inducing factor
      • Fibroblast growth factor 23 N-terminal peptide
      • Fibroblast growth factor 23 C-terminal peptide
      Background InformationFibroblast growth factor 23 (FGF-23) is also called Phosphatonin and Tumor-derived hypophosphatemia-inducing factor. FGF-23 belongs to the heparin-binding growth factors family and has several important functions including: regulation of phosphate homeostasis, inhibition of renal tubular phosphate transport, upregulation of EGR1 expression, regulation of vitamin-D metabolism, and negative regulation of osteoblast differentiation and matrix mineralization. FGF-23 is expressed in osteogenic cells, adult trabecular bone, osteocytes and flattened bone-lining cells (inactive osteoblasts). Defects in FGF23 can lead to autosomal dominant hypophosphataemic rickets (ADHR) and hyperphosphatemic familial tumoral calcinosis (HFTC).
      References
      Product Information
      FormatPurified
      Control
      • Human salivary gland tissue lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-FGF23 Antibody, clone 278-2 is a mouse monoclonal antibody & validated for use in western blotting.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: 2 µg from a representative lot detected FGF23 in Jurkat and human PMBC cells.
      Biological Information
      ImmunogenCorresponding to human FGF23.
      Clone278-2
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FGF23
      • HYPF
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight~25 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human salivary gland tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected FGF23 in 10 µg of human salivary gland tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS460 04053252921902

      Documentation

      Anti-FGF23 Antibody, clone 278-2 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-FGF23 Antibody, clone 278-2 Certificates of Analysis

      TitleLot Number
      Anti-FGF23, clone 278-2 - 3242718 3242718
      Anti-FGF23, clone 278-2 - 3385855 3385855
      Anti-FGF23, clone 278-2 - 3600709 3600709
      Anti-FGF23, clone 278-2 - Q2257010 Q2257010
      Anti-FGF23, clone 278-2 -2647563 2647563
      Anti-FGF23, clone 278-2 -2679506 2679506
      Anti-FGF23, clone 278-2 -2745862 2745862
      Anti-FGF23, clone 278-2 Monoclonal Antibody 3058493
      Anti-FGF23, clone 278-2 Monoclonal Antibody 3091969