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ABN999 Anti-Gustducin alpha-3 chain

Anti-Gustducin alpha-3 chain Antibody is an antibody against Gustducin alpha-3 chain for use in Immunohistochemistry and Immunocytochemistry.

Anti-Gustducin alpha-3 chain MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Gene Symbol: GNAT3 UniProt Number: A8MTJ3
ABN999
100 µg  
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      Overview

      Replacement Information

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN999
      DescriptionAnti-Gustducin alpha-3 chain
      Alternate Names
      • Gustducin alpha-3 chain
      • Guanine nucleotide-binding protein G(t) subunit alpha-3
      Background InformationGustducin alpha-3 chain is a G protein alpha subunit of the taste receptors and it plays a critical role in bitter, sweet and umami (MSG) taste transduction. Gustducin alpha-3 chain operates via the cGMP-phosphodiesterase signaling pathway and is mediated with calcium. Gustducin alpha-3 chain also functions in lumenal sugar sensors in the gut and may modulate the gut capacity to absorb sugars and thus play roles in malabsorption syndromes and diet related disorders including diabetes type II and obesity. Gustducin alpha-3 chain is localized to the cytoplasm and plasmalemmal being a G protein subunit. Gustducin alpha-3 chain is expressed in tastebuds and in the gut in enteroendocrine L cells, and surprisingly in spermatozoa.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Gustducin alpha-3 chain Antibody is an antibody against Gustducin alpha-3 chain for use in Immunohistochemistry and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected Gustducin alpha-3 chain in human ileum and rat testis tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Gustducin alpha-3 chain near the C-terminal.
      EpitopeNear C-terminal
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      Species Reactivity NoteHuman, Rat. Predicted to react with Bovine, Mouse, Hamster, Chimpanzee based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • GNAT3
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~50 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human tongue tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Gustducin alpha-3 chain in 10 µg of human tongue tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN999 04055977135275