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07-2108 Anti-Mechano Growth Factor (MGF) Antibody

Anti-Mechano Growth Factor (MGF) Antibody is an antibody against Mechano Growth Factor (MGF) for use in Immunohistochemistry (Paraffin), Western Blotting, Immunofluorescence.

Anti-Mechano Growth Factor (MGF) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: Igf1, Igf-1 UniProt Number: P05017
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07-2108
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HIH(P), WB, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number07-2108
      DescriptionAnti-Mechano Growth Factor (MGF) Antibody
      Alternate Names
      • Mechano Growth Factor
      • MGF
      • Insulin-like growth factor I
      • IGF-I
      • Somatomedin
      Background InformationMechano growth factor (MGF) is initially produced as a precursor (pro-MGF) from an mRNA species containing exons 5 and 6 of the IGF-I gene as a result of alternate splicing of the pro-IGF-1 mRNA in response to mechanical stimuli, such as tenectomy or eletrical stimulation. Exon 5 sequence-containing IGF-1 mRNA or the protein product is referred to as MGF, or Eb in rodents and Ec in human (PMID 20130113). Cat. no. 07-2108, Anti-Mechano Growth Factor (MGF), recognizes both pro- and mature MGF, but not IGF-I.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Mechano Growth Factor (MGF) Antibody is an antibody against Mechano Growth Factor (MGF) for use in Immunohistochemistry (Paraffin), Western Blotting, Immunofluorescence.
      Key Applications
      • Immunohistochemistry (Paraffin)
      • Western Blotting
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Mechano Growth Factor (MGF) in human prostate cancer and human cerebellum tissue.
      Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Mechano Growth Factor (MGF) in MGF recombinant protein (Heidi Scrable, University of Virginia).
      Immunofluorescence Analysis: A 1:5,000 dilution from a representative lot detected Mechano Growth Factor (MGF) in mouse hypothalamus cells (Heidi Scrable, University of Virginia).
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the E peptide domain of mouse Mechano Growth Factor (MGF).
      EpitopeE peptide domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis antibody does not cross-react with IGF1.
      Species Reactivity
      • Mouse
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Igf1
      • Igf-1
      Purification MethodAffinity
      UniProt Number
      Molecular Weight~15/8 kDa observed.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in human cerebral cortex tissue.

      Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Mechano Growth Factor (MGF) in human cerebral cortex tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      07-2108 04055977144987