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ABE556 Anti-Methyltransferase-like protein 13 Antibody

This Anti-Methyltransferase-like protein 13 Antibody is validated for use in western blotting & IP for the detection of Methyltransferase-like protein 13.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: METTL13, KIAA0859 UniProt Number: Q8N6R0
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ABE556
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IPRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE556
      DescriptionAnti-Methyltransferase-like protein 13 Antibody
      Alternate Names
      • Methyltransferase-like protein 13
      Background InformationThe protein named Methyltransferase-like protein 13 and encoded by the gene METTL13/KIAA0859, acts as a methyltransferase that is often up regulated in tumor tissue. Interestingly polymorphisms in the gene for METTL13 have also been associated with post-partum depression. Other members of this family catalyze important methylation reactions including the methylation of 7-methylguanosine in tRNA metabolism. Methyltransferase-like protein 13 is just one of several hundred family members and its expression is associated with many important events during embryonic development, growth and maturation but its actual function is still being discovered. Methyltransferase-like protein 13 is one of many genes that is highly conserved in eukaryotic development from worms to humans, thus its function is likely critical to some aspect of mammalian homeostasis.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Methyltransferase-like protein 13 Antibody is validated for use in western blotting & IP for the detection of Methyltransferase-like protein 13.
      Key Applications
      • Western Blotting
      • Immunoprecipitation
      Application NotesImmunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated Methyltransferase-like protein 13 in 500 µg of SK-OV-3 cell lysate.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Methyltransferase-like protein 13.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody witll detect isoforms 1, 2, 3, and 4 based on immunogen design.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Chimpanzee, Primate based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • METTL13
      • KIAA0859
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~58 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in SK-OV-3 cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected Methyltransferase-like protein 13 in 10 µg of SK-OV-3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE556 04053252944611