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ABT70 Anti-WASH complex subunit 7 (SWIP) Antibody

Detect WASH complex subunit 7 (SWIP) using this Anti-WASH complex subunit 7 (SWIP) Antibody validated for use in IP.

Anti-WASH complex subunit 7 (SWIP) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeletal Signaling Gene Symbol: KIAA10331 UniProt Number: Q2M389
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ABT70
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIPRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT70
      DescriptionAnti-WASH complex subunit 7 (SWIP) Antibody
      Alternate Names
      • WASH complex subunit 7
      Background InformationWASH complex subunit 7 (SWIP) is a component of the WASH complex belonging to the WASH S7 family. The WASH complex is localized at early endosomal subdomains involved in the activation and recruitment the ARP 2/3 complex in order to stimulate actin polymerization and tubulin interaction. Through its interaction with FAM21, WASH plays a regulatory role in the retromer-mediated trafficking of vesicles. It is also involved in the tubule fission, components required in endosomal sorting processes as transport intermediates.
      References
      Product Information
      FormatPurified
      Control
      • HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect WASH complex subunit 7 (SWIP) using this Anti-WASH complex subunit 7 (SWIP) Antibody validated for use in IP.
      Key Applications
      • Immunoprecipitation
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human WASH complex subunit 7.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • KIAA10331
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting By similarity.

      SUBUNIT STRUCTURE: Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.

      SEQUENCE SIMILARITIES: Belongs to the WASHS7 family.

      SEQUENCE CAUTION: The sequence AAI10851.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

      The sequence BAA82985.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
      Molecular Weight~135 kDa observed.
      IgG heavy chain may be observed at approximately 50 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunoprecipitation/Western Blot Analysis in HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7.

      Immunoprecipitation/Western Blot Analysis: 5 µg/mL of this antibody detected WASH complex subunit 7 in 10 µg of HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT70 04053252642647

      Documentation

      Anti-WASH complex subunit 7 (SWIP) Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-WASH complex subunit 7 (SWIP) Antibody Certificates of Analysis

      TitleLot Number
      Anti-WASH complex subunit 7 (SWIP) 2476803
      Anti-WASH complex subunit 7 (SWIP) - NRG1811385 NRG1811385
      Anti-WASH complex subunit 7 (SWIP) - NRG1812597 NRG1812597
      Anti-WASH complex subunit 7 (SWIP) - 3237509 3237509
      Anti-WASH complex subunit 7 (SWIP) - 3610575 3610575
      Anti-WASH complex subunit 7 (SWIP) - NRG1811385 NRG1811385
      Anti-WASH complex subunit 7 (SWIP) - NRG1812597 NRG1812597
      Anti-WASH complex subunit 7 (SWIP) -2757874 2757874
      Anti-WASH complex subunit 7 (SWIP) Polyclonal Antibody 3019778