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14-778M PP5, active

PP5, active MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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14-778M
250 µg  Also available in 10μg size as catalog # 14-778 and in 250 μg as catalog # 14-778M.
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      Overview

      Replacement Information
      Description
      Catalogue Number14-778M
      Trade Name
      • Upstate
      DescriptionPP5, active
      OverviewThis protein is a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family.
      Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine
      residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of
      this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
      References
      Product Information
      PresentationProtein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
      Quality LevelMQ100
      Applications
      Key Applications
      • Phosphatase Assay
      Biological Information
      SourceN-terminal GST-tagged, recombinant, full length, human PP5, expressed in E. coli cells.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • PP5
      • PPP5C
      • PPP5
      • PPT
      Purification MethodPurified using glutathione agarose.
      UniProt Number
      Molecular Weight83.8 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by the release of phosphate from the substrate 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10μg size as catalog # 14-778 and in 250 μg as catalog # 14-778M.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-778M 04053252738982

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      14-778 PP5, active Show Pricing & Availability

      Product Families

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
      Learn More >>

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Phosphatases
      Life Science Research > Proteins and Enzymes > Purified Phosphatases