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GF313 TGF- α Protein, Human Recombinant Animal Free

Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor & stimulates the proliferation of a wide range of epidermal & epithelial cells. Manufactured using all non-animal reagents.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P01135 Entrez Gene Number: NM_001099691.1, NM_003236.2
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GF313
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      SourcePurity
      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF313
      DescriptionTGF- α Protein, Human Recombinant Animal Free
      Alternate Names
      • Transforming growth factor alpha
      • TGFa
      • TGF alpha
      • EGF-like TGF
      • TGF type 1
      Background InformationTransforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
      References
      Product Information
      Formulation
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationTransforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor & stimulates the proliferation of a wide range of epidermal & epithelial cells. Manufactured using all non-animal reagents.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityChicken, Mouse, Rat
      Entrez Gene Number
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      GF313 04053252691492

      Documentation

      TGF- α Protein, Human Recombinant Animal Free SDS

      Title

      Safety Data Sheet (SDS) 

      TGF- α Protein, Human Recombinant Animal Free Certificates of Analysis

      TitleLot Number
      Recombinant Animal Free -2537452 2537452
      Recombinant Animal Free -2721519 2721519
      Recombinant Animal Free Human TGF- #945; - Q2007166 Q2007166
      Recombinant Animal Free Human TGF- α - 3192463 3192463
      Recombinant Animal Free Human TGF- α - 3351207 3351207
      Recombinant Animal Free Human TGF- α - 3498489 3498489
      Recombinant Animal Free Human TGF- α - 3601701 3601701
      Recombinant Animal Free Human TGF- α - 3761065 3761065
      Recombinant Animal Free Human TGF- α - 3781050 3781050
      Recombinant Animal Free Human TGF- α - 3850545 3850545
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      Brochure

      Title
      New Products: Volume 3, 2012

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      Categories

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      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors