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203702 Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli

203702
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥97% by HPLC
      Description
      OverviewRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons. Structurally and functionally related to nerve growth factor. Its actions are mediated via the TrkB receptor.
      Catalogue Number203702
      Brand Family Calbiochem®
      SynonymsrhBDNF
      References
      ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
      Leibrock, J., et al. 1989. Nature 341, 149.
      Product Information
      FormLyophilized
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      Brain Derived Neurotrophic Factor, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      203702

      References

      Reference overview
      Erickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
      Leibrock, J., et al. 1989. Nature 341, 149.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-February-2019 JSW
      SynonymsrhBDNF
      DescriptionRecombinant, human brain drived neurotrophic factor expressed in E. coli. Promotes survival and growth of neurons in the central nervous system. Sequence analysis indicates that brain derived neurotrophic factor is structurally and functionally related to nerve growth factor. mRNA for brain derived neurotrophic factor is found predominantly in the central nervous system, whereas mRNA for nerve growth factor is also found in many non-CNS tissues.
      FormLyophilized
      Purity≥97% by HPLC
      Biological activitySupports survival of rat basal forebrain primary septal cultured neurons. Induces choline acetyltransferase (EC₅₀ = 50 ng/ml)
      SolubilityReconstitute to a concentration of ≥10 µg/ml with sterile distilled H₂O or aqueous buffers. For more dilute solutions, add a stabilizing protein such as 0.1% BSA or HSA.
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
      Toxicity Standard Handling
      Merck USA index14, 6487
      ReferencesErickson, J.T., et al. 1996. J. Neurosci. 16, 5361.
      Leibrock, J., et al. 1989. Nature 341, 149.