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208690 Calmodulin, Bovine Brain

208690
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      A ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin purified from bovine brain.

      Note: 1 KU = 1000 units.
      Note: this product cannot be used for animal treatment, in vivo research, or any contact procedure with livestock.
      Catalogue Number208690
      Brand Family Calbiochem®
      SynonymsCaM, Ca2+/Calmodulin
      References
      ReferencesCarl, A., et al. 1990. J. Physiol. 429, 205.
      Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
      Cheung, W.T. 1979. Science 207, 19.
      Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
      Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
      Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.
      Product Information
      CAS number73298-54-1
      Unit of DefinitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
      FormLyophilized
      FormulationLyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Specific Activity≥12,500 units/mg protein
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Calmodulin, Bovine Brain SDS

      Title

      Safety Data Sheet (SDS) 

      Calmodulin, Bovine Brain Certificates of Analysis

      TitleLot Number
      208690

      References

      Reference overview
      Carl, A., et al. 1990. J. Physiol. 429, 205.
      Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
      Cheung, W.T. 1979. Science 207, 19.
      Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
      Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
      Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-February-2010 JSW
      SynonymsCaM, Ca2+/Calmodulin
      DescriptionA ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin purified from bovine brain.

      Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
      FormLyophilized
      FormulationLyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
      CAS number73298-54-1
      Purity≥95% by SDS-PAGE
      Specific activity≥12,500 units/mg protein
      Unit definitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
      SolubilityAqueous buffers or H₂O
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
      Toxicity Standard Handling
      Merck USA index14, 1719
      ReferencesCarl, A., et al. 1990. J. Physiol. 429, 205.
      Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res. 10, 417.
      Cheung, W.T. 1979. Science 207, 19.
      Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
      Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg. 15, 47.
      Watterson, A., et al. 1976. J. Biol. Chem. 251, 4501.