407129 D-myo-Inositol 1,4,5-Trisphosphate, 3-Deoxy-3-fluoro-, Hexasodium Salt - CAS 129365-68-0 - Calbiochem

407129
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₆H₈FO₁₄P₃ · 6Na129365-68-0
      Description
      Overview

      This product has been discontinued.



      Equipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine, hence it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. May be a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.

      Catalogue Number407129
      Brand Family Calbiochem®
      Synonyms3-F-Ins(1,4,5)P₃, 6Na
      References
      ReferencesRubinstein, E., et al. 1992. Blood 79, 2901.
      Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc. 112, 7403.
      Bartha, K., et al. 1989. Biochem. J. 263, 149.
      Product Information
      CAS number129365-68-0
      ATP CompetitiveN
      FormWhite crystalline solid
      Hill FormulaC₆H₈FO₁₄P₃ · 6Na
      Chemical formulaC₆H₈FO₁₄P₃ · 6Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetReleasing intracellular calcium
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      D-myo-Inositol 1,4,5-Trisphosphate, 3-Deoxy-3-fluoro-, Hexasodium Salt - CAS 129365-68-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      D-myo-Inositol 1,4,5-Trisphosphate, 3-Deoxy-3-fluoro-, Hexasodium Salt - CAS 129365-68-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      407129

      References

      Reference overview
      Rubinstein, E., et al. 1992. Blood 79, 2901.
      Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc. 112, 7403.
      Bartha, K., et al. 1989. Biochem. J. 263, 149.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-July-2008 RFH
      Synonyms3-F-Ins(1,4,5)P₃, 6Na
      DescriptionEquipotent to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine so it cannot be converted to Ins(1,3,4,5)P4 by the action of 3-kinases. May be a useful tool for studying the complex biochemical pathways in which InsP3 and InsP4 are closely interactive.
      FormWhite crystalline solid
      CAS number129365-68-0
      Chemical formulaC₆H₈FO₁₄P₃ · 6Na
      Structure formulaStructure formula
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesRubinstein, E., et al. 1992. Blood 79, 2901.
      Kozikowski, A.P., et al. 1990. J. Am. Chem. Soc. 112, 7403.
      Bartha, K., et al. 1989. Biochem. J. 263, 149.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Lipids > Phosphoinositides, Phospholipids and Related Products