317232 DMNQ

317232
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₂H₁₀O₄6956-96-3
      Description
      Overview

      This product has been discontinued.





      A cell-permeable, non-alkylating, non-thiol, adduct-forming, redox cycling quinone. Can be used to eliminate any mechanistic ambiguity involving redox cycling quinoids as the source of reactive oxidant species/oxidative stress in biological studies. DMNQ is also reported to result in either cell proliferation or apoptotic or necrotic cell death, depending upon the concentration used.
      Catalogue Number317232
      Brand Family Calbiochem®
      Synonyms2,3-Dimethoxy-1,4-naphthoquinone, DiMeNQ
      References
      ReferencesDooley, C.T., et al. 2004. J. Biol. Chem. 279, 22284.
      Seung, S.A., et al. 1998. Chem. Biol. Interact. 113, 133.
      Breton, J., et al. 1994. Biochemistry 33, 12405.
      Dypbukt, J.M., et al. 1994. J. Biol. Chem. 269, 30553.
      Shi, M.M., et al. 1994. J. Biol. Chem. 269, 26512.
      Product Information
      CAS number6956-96-3
      FormCrystalline solid
      Hill FormulaC₁₂H₁₀O₄
      Chemical formulaC₁₂H₁₀O₄
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      DMNQ Certificates of Analysis

      TitleLot Number
      317232

      References

      Reference overview
      Dooley, C.T., et al. 2004. J. Biol. Chem. 279, 22284.
      Seung, S.A., et al. 1998. Chem. Biol. Interact. 113, 133.
      Breton, J., et al. 1994. Biochemistry 33, 12405.
      Dypbukt, J.M., et al. 1994. J. Biol. Chem. 269, 30553.
      Shi, M.M., et al. 1994. J. Biol. Chem. 269, 26512.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-December-2009 RFH
      Synonyms2,3-Dimethoxy-1,4-naphthoquinone, DiMeNQ
      DescriptionA redox cycling quinone that is a novel, non-alkylating, non-thiol, adduct-forming compound. Can be used to eliminate any mechanistic ambiguity involving redox cycling quinoids as the source of reactive oxidant species/oxidative stress in biological studies. DMNQ is also reported to result in either cell proliferation or apoptotic or necrotic cell death, depending on the concentration used.
      FormCrystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number6956-96-3
      Chemical formulaC₁₂H₁₀O₄
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDooley, C.T., et al. 2004. J. Biol. Chem. 279, 22284.
      Seung, S.A., et al. 1998. Chem. Biol. Interact. 113, 133.
      Breton, J., et al. 1994. Biochemistry 33, 12405.
      Dypbukt, J.M., et al. 1994. J. Biol. Chem. 269, 30553.
      Shi, M.M., et al. 1994. J. Biol. Chem. 269, 26512.