K1750
α-Ketoglutaric acid
≥98.5% (NaOH, titration)
Synonym(s):
2-Oxoglutaric acid, 2-Oxopentanedioic acid
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About This Item
Linear Formula:
HOOCCH2CH2COCOOH
CAS Number:
Molecular Weight:
146.10
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
EC Number:
206-330-3
Beilstein/REAXYS Number:
1705689
MDL number:
Quality Segment
assay
≥98.5% (NaOH, titration)
form
powder
solubility
water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
2-8°C
SMILES string
OC(=O)CCC(=O)C(O)=O
InChI
1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI key
KPGXRSRHYNQIFN-UHFFFAOYSA-N
General description
α-Ketoglutaric acid (α-KG) is produced in the tricarboxylic acid cycle.
Application
α-Ketoglutaric acid (α-KG) has been used:
- to study its effects on swine fecal microflora in an in vitro fermentation system
- to study its effects on the activation of CD8+ T-cells
- as a substrate in glutamate oxaloacetate transaminase (GOT2) mitochondrial lysate assay
Biochem/physiol Actions
α-Ketoglutaric acid (α-KG) has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries.
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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