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News Release
August 3, 2016
Karen Tiano:
+1 978-495-0093

Merck Expands Portfolio of Certified Reference Materials for Applied Diagnostics and Testing
  • Two new products support the identification of the industry-standard alcohol biomarker with high sensitivity
  • Seven new products ensure accurate identification of omega-3 and omega-6 fatty acids for diagnostic testing

Darmstadt, Germany, August 3, 2016 Merck, a leading science and technology company, today announced the expansion of its portfolio of Cerilliant® certified reference materials (CRMs) with nine new Certified Spiking Solutions® used in laboratories around the world. The premade stock solutions can be spiked into matrices to create accurate controls and calibrators for applied diagnostics and testing, ensuring reliability in the identification and quantification of drugs and endogenous biomarkers.

“Our portfolio of certified reference materials leverages the latest research and techniques from around the world to meet the ever-changing needs of the health care industry,” said Theresa S. Creasey, Head of Strategy, Marketing and Innovation at the life science business of Merck. “Merck’s commitment to highly accurate and reliable starting materials helps our customers stay ahead of the curve, ultimately supporting the best possible care and outcomes for patients.”

The new additions to the Cerilliant® product line include two Certified Spiking Solutions® of phosphatidylethanol (PEth), an alcohol biomarker with high sensitivity appropriate for determining moderate to heavy alcohol consumption.1 Due to its superior sensitivity and specificity, PEth is now widely used to detect recent drinking. To date, a false positive blood PEth test result has yet to be reported.2

Seven new Certified Spiking Solutions® of five Omega-3 fatty acids and two Omega-6 fatty acids have also been added to the product line. These fatty acids, the most commonly monitored in clinical and diagnostic testing applications, play a critical role in conditions including coronary heart disease, diabetes mellitus and cancer.3,4 Fatty acid levels are evaluated using mass spectrometry to determine patients’ risk of coronary events, to diagnose essential fatty acid deficiency or to monitor patient response with  therapies or dietary supplements.3,4

Cerilliant® certified reference solutions are manufactured and authorized to ensure the highest level of accuracy. Solutions are used in quantitative mass spectrometry-based applications that range from therapeutic drug monitoring to diagnostic testing and from endocrinology to pharmaceutical research, clinical toxicology and forensic analysis. Merck manufactures a comprehensive list of parent drug, metabolite and internal standard Certified Spiking Solutions® used for clinical diagnostic test applications of immunosuppressants, bile acids, vitamins, steroids and hormones, catecholamines, cardiac drugs, antidepressants and pain management drugs.



About Merck
Merck is a leading science and technology company in healthcare, life science and performance materials. Around 50,000 employees work to further develop technologies that improve and enhance life – from biopharmaceutical therapies to treat cancer or multiple sclerosis, cutting-edge systems for scientific research and production, to liquid crystals for smartphones and LCD televisions. In 2015, Merck generated sales of € 12.85 billion in 66 countries.

Founded in 1668, Merck is the world's oldest pharmaceutical and chemical company. The founding family remains the majority owner of the publicly listed corporate group. The company holds the global rights to the Merck name and brand. The only exceptions are the United States and Canada, where the company operates as EMD Serono, MilliporeSigma and EMD Performance Materials.