Metabolism Biomarker Assay Kits Using Luminex® Technology

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Related Resources: Analyte Quarterly | Application Notes | Posters

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Measure endocrine and metabolism biomarkers with MILLIPLEX® MAP multiplexed assay kits. Obesity, diabetes and associated conditions, under the umbrella of metabolic syndrome, are urgent health issues. Key features of metabolic syndrome include: These symptoms are risk factors for atherosclerosis, coronary heart disease, type 2 diabetes, kidney disease, and even premature death. Adults with metabolic syndrome show inflammation, which may be linked to metabolism via dysregulated adipocyte production of pro- and anti-inflammatory factors. Consequently, biomarkers for metabolic syndrome include cytokines, acute phase proteins, diabetes and obesity-related hormones, as well as other endocrine biomarkers. With our expanding portfolio of assays to detect endocrine biomarkers, hormones, insulin-like growth factors and binding proteins, myokines, bone metabolism, and more, Merck is the leader in advancing your research of metabolic syndrome.

Bring your metabolism biomarkers to life with MILLIPLEX® MAP Multiplex Assays

Bead-based multiplex assays enable precise, multiparametric analysis of diseases and underlying processes. Our MILLIPLEX® MAP multiplex metabolism biomarker assay kits enable you to simultaneously quantify nearly 400 analytes across several species.

Based on Luminex xMAP® technology, our analytically validated assay kits provide:

• Standards validated to match reference lots
• Serum matrix for generating standard curves that accurately simulate conditions of native analyte conditions in serum or plasma
• In-assay controls
• Detection antibody cocktails to ensure consistent performance regardless of plex size

Some examples of the multiplex assay analytes in our portfolio are listed below.

Diabetes, Metabolic and Gut Hormones*:

Gut hormones regulate gut motility and secretion, pancreatic islet hormone secretion, food intake and energy expenditure.

Glucagon	GLP-1	Leptin
C-Peptide	GIP	Insulin
PYY	Ghrelin	Amylin

*only selected analytes listed

• Browse all MILLIPLEX® Diabetes, Metabolic and Gut Hormone Panels

Adipokines*:

Hormones called adipokines regulate appetite and energy balance, insulin sensitivity, and lipid metabolism.

Adiponectin	IL-1β	IL-6
MCP-1	PAI-1	Resistin
TNF-α	Leptin	Adiponectin

*only selected analytes listed

• Browse all MILLIPLEX® Panels for Adipokines, Adipocytes, Adiponectin and IGF

Bone and Myokine Biomarkers*:

Myostatin	Oncostatin M	Osteoprotegerin
Irisin	Apelin	ACTH
Musclin	Osteocalcin	DKK1
SPARC	Osteopontin	SOST

*only selected analytes listed

• Browse all MILLIPLEX® Bone and Myokine Panels

Hormones of Reproduction, Development and Homeostasis*:

Testosterone	Estradiol	Corticosterone
TSH	T3	AgRP

*only selected analytes listed

• Browse all MILLIPLEX® Panels for Pituitary, Thyroid, Stress and Reproductive Hormones

To expand the power of your metabolism and endocrinology research, we also offer MILLIPLEX® MAP multiplex assays for:

• Inflammation and Immunology
• Cardiovascular Disease
• Neuroscience
• Cellular metabolism and signaling pathways (Intracellular Assays)

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Download the Analyte Quarterly brochure for a complete, updated list of assays.

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