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HGAMMAG-301K

MILLIPLEX® Human Immunoglobulin Isotyping Panel

Configurable Human Immunoglobulin Isotyping 6-Plex Panel

동의어(들):

Human Ig isotype multiplex panel, Human immune globulin multiplex panel, Human immunoglobulin multiplex kit, Luminex® human immunoglobulin immunoassay, Millipore Human immunoglobulin panel

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

제품 이름

MILLIPLEX® Human Immunoglobulin Isotyping Panel,

Quality Segment

200

description

Configurable Human Immunoglobulin Isotyping 6-Plex Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 88-99%, sensitivity: 0.08 ng/mL
(IgG4), sensitivity: 0.09 ng/mL
(IgG3), sensitivity: 0.47 ng/mL
(IgM), sensitivity: 1.5 ng/mL
(IgA), sensitivity: 10 ng/mL
(IgG1), sensitivity: 85 ng/mL
(IgG2), standard curve range: 0.2-150 ng/mL
(IgG3), standard curve range: 0.4-300 ng/mL
(IgG4), standard curve range: 14-10,000 ng/mL
(IgG1), standard curve range: 2.1-1,500 ng/mL
(IgA), standard curve range: 3.4-2,500 ng/mL
(IgM), standard curve range: 41-30,000 ng/mL
(IgG2)

technique(s)

multiplexing: suitable

input

serum
plasma
cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Produced by plasma cells and lymphocytes, immunoglobulins (antibodies) are critically involved in immune response, attaching to antigens, and playing a role in their destruction. Immunoglobulins (Ig) can be classified by isotype, classes that differ in function and antigen response due to structure variability. Five major isotypes have been identified in placental mammals: IgM, IgG, IgA, IgE and IgD (B-cell receptor) – all found in normal individuals. Immunoglobulin-deficiency disorders, such as autoimmune disease, some GI conditions, and malignancies, are characterized by specific isotype deficiencies or varying concentrations of one or more isotypes. Disease states can range from the absence of one isotype class or subclass to a total deficiency of immunoglobulin classes. In addition, isotyping applications include analyzing hybridomas during antibody generation and vaccine development.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: IgG1, IgG2, IgG3, IgG4, IgA, IgM

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Comprehensive Isotyping: Measures multiple human immunoglobulin classes and subclasses (IgG1, IgG2, IgG3, IgG4, IgA, IgM) in a single assay, providing a complete overview of the immune response.
  • Enhanced Research Capabilities: By providing a detailed analysis of immunoglobulin isotypes, researchers can better understand immune responses in various conditions, including autoimmune diseases and malignancies.
  • Quick Turnaround: Assay run time of just one day allows for timely results, facilitating faster research progress.
  • Standardization and Controls: Includes multi-immunoglobulin standard and positive control to ensure assay reliability and accuracy.
  • Increased Productivity: The multiplex nature of the assay significantly reduces the time and resources needed to assess multiple analytes, allowing researchers to focus on data interpretation and application.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

저장 등급

10 - Combustible liquids

wgk

WGK 3

시험 성적서(COA)

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