- Facile oxidation of electron-poor benzo[b]thiophenes to the corresponding sulfones with an aqueous solution of H2O2 and P2O5.
Facile oxidation of electron-poor benzo[b]thiophenes to the corresponding sulfones with an aqueous solution of H2O2 and P2O5.
Chemical communications (Cambridge, England) (2010-03-18)
Dyeison Antonow, Teresa Marrafa, Irfaan Dawood, Tauheed Ahmed, Mohammad R Haque, David E Thurston, Giovanna Zinzalla
PMID20234935
ABSTRACT
A facile oxidation for the clean conversion of benzo[b]thiophenes to their corresponding sulfones is described employing an aqueous solution of H(2)O(2) and P(2)O(5); the solution can be prepared and stored on a multi-gram scale with a shelf-life of up to two weeks.
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