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122564

Mechlorethamine hydrochloride

Name: Mechlorethamine hydrochloride
Brand: ALDRICH

98%

Synonyme(s) :

2-Chloro-N-(2-chloroethyl)-N-methylethanamine, N-Methylbis(2-chloroethyl)amine hydrochloride, Bis(2-Chloroethyl)methylamine, Bis(2-chloroethyl)methylamine, MBA hydrochloride, NM, Nitrogen mustard

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A propos de cet article

Formule linéaire :

(ClCH₂CH₂)₂NCH₃·HCl

Numéro CAS:

55-86-7

Poids moléculaire :

192.51

NACRES:

NA.22

PubChem Substance ID:

24847496

UNSPSC Code:

12352100

EC Number:

200-246-0

MDL number:

MFCD00012517

Assay:

98%

Form:

solid

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Propriétés

Quality Segment

100

assay

98%

form

solid

mp

108-111 °C (lit.)

solubility

H₂O: very soluble, alcohol: soluble

functional group

amine, chloro

SMILES string

Cl.CN(CCCl)CCCl

InChI

1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H

InChI key

QZIQJVCYUQZDIR-UHFFFAOYSA-N

Description

Application

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

Biochem/physiol Actions

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

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pictograms

GHS06,GHS08,GHS05

signalword

Danger

hcodes

H300 + H310,H314,H340,H350,H360D

pcodes

P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1B - Skin Corr. 1B

Classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c