Operation and Optimization of
Normal Flow Filtration (NFF)
One and a Half Day Course
Course Description
Using a combination of theory and hands-on instruction, workshop and participants will understand the key principles and techniques involved in the development and optimization of normal flow filtration processes. This training candidates on the knowledge and skills to prepare and perform normal flow filtration operation. This course covers normal flow filtration from small scale to pilot scale in biopharmaceutical process.
Course ID: TRADVNFF
Dates & Venue
Learning Goals
- Understand basic normal flow filtration concepts and terminology.
- Understand the steps required to operate and maintain normal flow filtration
- Understand normal flow filtration processes such as clarification, pre-filtration, virus filtration and aseptic filtration.
- Construction and operation of normal flow filtration modules.
- Understand how to reinstate normal flow filtration equipment after operation
Who should attend?
This course is designed for R&D scientists and pilot and production departments who have responsibility for developing and implementing NFF processes in the pharmaceutical and biopharmaceutical industry.
What will you receive?
- A copy of the course materials.
- Protocol and results of laboratory sessions
- A certificate of attendance
Course Schedule and Program
Day 1
- Course Introduction
- Introduction of filtration in pharm and biopharm process
- Advanced topics in optimization, design and operation of NFF
- Practical Session #1: Sizing test by Constant pressure
(Set up, Flush, equilibration and operation Steps of small scale) - A Practical Guide to Vmax for NFF Filter Sizing
- Workshop : Optimize process by right filter selection
- Interpreting the test results from practical Session
Day 2
- NFF operation and Scale-up
- Practical Session #2: Operation and filtration of Pilot Scale
- Written Assessment
- Conclusion
Enrollment is Limited
Due to the hands-on nature of this course, enrollment is limited. We recommend early booking to ensure a place
Price
Please contact your local Merck representative or send an email to ilearn@merckgroup.com for a quote.