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852067 Fmoc-Arg(Pbf)-OH

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
154445-77-9C₃₄H₄₀N₄O₇S648.77 g/mol

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                          Description
                          Catalogue Number852067
                          Replaces04-12-1145
                          Brand Family Novabiochem®
                          Alternate Names
                          • N-α-Fmoc-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
                          Background InformationThe standard derivative for the introduction of Arg in Fmoc SPPS [1, 2]. The Pbf side-chain protecting group is removed with TFA approximately 1-2 times faster than Pmc.

                          In the preparation of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH (852050).

                          The product number for this product was previously 04-12-1145.

                          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
                          References
                          Product Information
                          CAS number154445-77-9
                          Hill FormulaC₃₄H₄₀N₄O₇S
                          Molar Mass648.77 g/mol
                          HS Code2935 90 29
                          Structure formula ImageStructure formula Image
                          Quality LevelMQ400
                          Applications
                          ApplicationFmoc-Arg(Pbf)-OH Novabiochem®. CAS 154445-77-9, molar mass 648.78 g/mol.
                          Biological Information
                          Physicochemical Information
                          Melting Point>65 °C
                          Dimensions
                          Materials Information
                          Toxicological Information
                          Safety Information according to GHS
                          Storage class10 - 13 Other liquids and solids
                          WGKWGK 3 highly hazardous to water
                          Safety Information
                          Product Usage Statements
                          Storage and Shipping Information
                          StorageStore at -10°C to -25°C.
                          Packaging Information
                          Transport Information
                          Supplemental Information
                          Specifications
                          Color (visual)white to off white
                          Appearance of substance (visual)powder
                          Color index (0,5 M in DMF)≤ 150 Hazen
                          Identity (IR)passes test
                          Enantiomeric purity≥ 99.8 % (a/a)
                          Purity (HPLC)≥ 99.0 % (a/a)
                          Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
                          Fmoc-ß-Ala-Arg(Pbf)-OH (HPLC)≤ 0.1 % (a/a)
                          Fmoc-Arg(Pbf)-Arg(Pbf)-OH (HPLC)≤ 0.1 % (a/a)
                          Fmoc-Arg-OH (HPLC)≤ 0.1 % (a/a)
                          Assay free amino acid (HPLC)≤ 0.2 %
                          Purity (TLC(011C))≥ 98 %
                          Purity (TLC(157B))≥ 98 %
                          Solubility (12,5 mmol in 25 ml DMF)clearly soluble
                          Assay (acidimetric)≥ 90.0 %
                          Water (K. F.)≤ 2.0 %
                          Ethyl acetate (HS-GC)≤ 1.0 %
                          Acetate (IC)≤ 0.02 %
                          For TLC-Systems see our General Catalog
                          Global Trade Item Number
                          Catalogue Number GTIN
                          8520670005 04027269087982
                          8520670025 04027269087999
                          8520670100 04027269088002
                          8520670250 04027269207076
                          8520670500 04027269180492
                          8520671000 04027269180478

                          Documentation

                          Fmoc-Arg(Pbf)-OH SDS

                          Title

                          Safety Data Sheet (SDS) 

                          Citations

                          Title
                          • [1] L. A. Carpino, et al. (1993) Tetrahedron Lett., 34, 7829.
                          • [2] C. G. Fields, et al. (1993) Tetrahedron Lett., 34, 6661.