agonist
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508578 Sigma-AldrichTSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem
A 4'-chloro derivative of diazepam that lacks affinity for GABA-A receptors, but can serve as a ligand for the peripheral benzodiazepine receptor.
681665 Sigma-AldrichWnt Agonist - CAS 853220-52-7 - Calbiochem
Wnt Agonist, CAS 853220-52-7, is a cell-permeable, potent, and selective activator of Wnt signaling. Does not inhibit the activity of GSK-3β (IC50 greater than 60 µM).
681667 Sigma-AldrichWnt Agonist II, SKL2001 - CAS 909089-13-0 - Calbiochem
Wnt Agonist II, SKL2001, CAS 909089-13-0, upregulates β-catenin-regulated transcription by disrupting β-catenin & Axin interaction. Prevents β-catenin phosphorylation and proteasomal degradation.
648493 Sigma-AldrichTRPML Agonist, ML-SA1 - CAS 332382-54-4 - Calbiochem
The TRPML Agonist, ML-SA1 controls the biological activity of TRPML. This small molecule/inhibitor is primarily used for Biochemicals applications.
371706 Sigma-AldrichGPR40 Agonist - CAS 885101-89-3 - Calbiochem
The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications.
371725 Sigma-AldrichGPR43 (FFA2) Agonist - CAS 1208552-99-1 - Calbiochem
GPR43 (FFA2) Agonist is an allosteric agonist of FFA2 (GPR43). Displays a left-shifted acetate dose response (IC50 = 0.7 µM) & 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays.
554726 Sigma-AldrichREV-ERB Agonist II, SR9009 - Calbiochem
REV-ERB Agonist II, SR9009, CAS 1379686-30-2, acts as a specific REV-ERB-α/β agonist that exhibits a direct and reversible binding (Kd = 800 nM).
566660 Sigma-AldrichSmoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem
A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM).
119139 Sigma-AldrichAdenosine A₃ Receptor Agonist, 2-Cl-IB-MECA - CAS 163042-96-4 - Calbiochem
A highly selective agonist of adenosine A3 receptor (Ki = 330 pM)