The ultimate goal of most antisense research is to develop therapeutic agents for diseases such as diabetes, cancer, and HIV/ AIDS. Phosphorothioate oligonucleotides (commonly referred to as S-oligos) are often the molecules of choice because of their resistance to cellular nuclease degradation.
Assays that predict passive absorption of orally administered drugs have become increasingly important in the drug discovery process. As previously described by Faller and Kansy such assays provide rapid, low cost and automation friendly methods to measure a compound’s passive permeability.
Cancer research strives to not only identify the cause, but also methods for detection, treatment, and prevention. Learn more about our contributions to cancer research in academic and industrial settings.
Rooted in physiology and biochemistry, cell and development biology features an interdisciplinary approach to understand intracellular and extracellular dynamics.
Cell signaling refers to the stimuli-driven communication cascade between cells. Learn more about cell signaling processes and protocols to study complex cellular processes.
Immunology covers all aspects of the immune system, including physiological functioning and malfunctions, in all multicellular organisms. Learn more about our resources for immunology research including articles and protocols.