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1.06176

Methanol

greener alternative

BioRenewable, ≥99.9% (GC), suitable for LC-MS, LiChrosolv®

Synonym(s):

Methyl alcohol

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About This Item

Linear Formula:
CH3OH
CAS Number:
67-56-1
Molecular Weight:
32.04
UNSPSC Code:
12191502
NACRES:
NA.03
EC Index Number:
200-659-6
MDL number:
MFCD00004595
Beilstein/REAXYS Number:
1098229
Assay:
≥99.9% (GC)
Bp:
64.7 °C (lit.)
Vapor pressure:
128 hPa ( 20 °C), 410 mmHg ( 50 °C), 97.68 mmHg ( 20 °C)
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vapor density

1.11 (vs air)

Quality Level

100

vapor pressure

128 hPa ( 20 °C), 410 mmHg ( 50 °C), 97.68 mmHg ( 20 °C)

product line

LiChrosolv®

assay

≥99.9% (GC)

autoignition temp.

725 °F

expl. lim.

36 %

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.01% Water, ≤10 ppb Aluminium (Al), ≤10 ppb Calcium (Ca), ≤10 ppb Iron (Fe), ≤10 ppb Magnesium (Mg), ≤10 ppb Sodium (Na), ≤5 ppb Any further metal (ICP-MS), ≤5 ppb Potassium (K)

transmittance

210 nm, ≥35%, 220 nm, ≥60%, 230 nm, ≥75%, 260 nm, ≥98%

refractive index

n20/D 1.329 (lit.), n/D (n20/D 1.329)(lit.)

kinematic viscosity

0.54-0.59 cSt(20 °C)

bp

64.7 °C (lit.)

mp

−98 °C (lit.)

transition temp

flash point 9.7 °C

density

0.791 g/mL at 25 °C (lit.)

UV absorption

λ: 225 nm Amax: ≤0.170

suitability

suitable for HPLC, suitable for LC-MS

SMILES string

CO

format

neat

greener alternative category

Aligned

InChI

1S/CH4O/c1-2/h2H,1H3

InChI key

OKKJLVBELUTLKV-UHFFFAOYSA-N

General description

LiChrosolv® hypergrade is accurately tested for LC-MS suitability and meets all the requirements of modern LC-MS ionization methods (ESI/APCI - positive and negative mode). Thanks to their low level of ionic background and low ion suppression, LiChrosolv® hypergrade solvents provide high reproducibility and high ionization efficiency. The packaging material has been improved to meet LC-MS quality requirements perfectly.
This bio-based solvent for LC-MS offers the same precisionand reliability you trust, now with more sustainability.

  • Derived from renewable feedstocks with bio-carbon content certification
  • Similar chromatographic resolution, reproducibility, and baseline stability
  • Drop-in replacement: no method redevelopment required
We are committed to bringing you greener alternative products that adhere to one or more of the 12 Principles of Greener Chemistry, and this bio-based (BioRenewable) product aligns with the principles of Safer Solvents and Auxiliaries and Use of Renewable Feedstocks.

Application

  • Mobile Phase in HPLC: Widely utilized as a polar solvent in both reversed-phase and normal-phase HPLC, suitable for various types of analytes.
  • Gradient Elution: Ideal for gradient elution techniques, enhancing the resolution and separation efficiency of complex mixtures.
  • Pharmaceutical Quality Control: Used in the quality control of pharmaceutical products to analyze formulations, stability, and degradation products.
  • Food and Beverage Analysis: Employed in HPLC for the analysis of additives, preservatives, and flavor compounds in food and beverage samples.
  • Natural Product Analysis: Utilized in the separation and characterization of natural products, such as alkaloids and flavonoids, from plant extracts.

Features and Benefits

  • High Purity: Formulated with minimal impurities, ensuring reliable and reproducible results essential for sensitive analytical applications.
  • Excellent UV Transparency: Provides optimal UV transmittance, facilitating accurate detection and enhancing sensitivity in HPLC analyses.
  • Low Evaporation Residue: Minimizes contamination risk, leading to cleaner separations and improved analytical reliability.
  • Batch-to-Batch Consistency: Ensures uniform quality and performance across different production batches, enhancing reproducibility, and confidence in analytical results.

Analysis Note

  • Evaporation Number: 1.9
  • Purity (GC): ≥ 99.9 %
  • Identity (IR): conforms
  • Evaporation residue: ≤ 1.0 mg/l
  • Gradient grade (at 220 nm): ≤ 2.0 mAU
  • Gradient grade (at 235 nm): ≤ 1.0 mAU
  • Fluorescence (as quinine at 254 nm): ≤ 1.0 ppb
  • Fluorescence (as quinine at 365 nm): ≤ 0.5 ppb
  • Transmission (at 210 nm): ≥ 35 %
  • Transmission (at 220 nm): ≥ 60 %
  • Transmission (at 230 nm): ≥ 75 %
  • Transmission (from 260 nm): ≥ 98 %
  • Suitable for LC-MS; Intensity of background mass peak based on reserpine(APCI/ESI positive): ≤ 2 ppb
  • Suitable for LC-MS; Intensity of background mass peak based on reserpine(APCI/ESI negative): ≤ 20 ppb Filtered by 0.2 µm filter.

Other Notes

Available with Data Matrix Code

This high-quality LCMS-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batchnumber, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.
Bio-Based LC-MS Solvents

LiChrosolv™ bio-based solvents are derived from renewable feedstocks and verified through bio-carbon content certification. They provide comparable chromatographic performance to conventional solvents; same resolution, reproducibility, and baseline stability; and function as drop-in replacements requiring no method redevelopment.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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