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Durapore® 0.1 µm and 0.22 µm Cartridge Filters

A trusted name in the industry for over 25 years, The Durapore membrane contributes to clean processes due to low extractables, broad chemical compatibility, and its non-fiber releasing properties.

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Spezifikationen

Bestellinformationen

Los
Durapore 0,22 µm · Adaptercode 0, 2-222 O-RingSortierung & Filter aufheben Show Filter
BestellnummerNominelle Filterelementlänge
CVGL01TP310 in. (25 cm) Preis & Verfügbarkeit
CVGL02TP320 in. (50 cm) Preis & Verfügbarkeit
CVGL03TP330 in. (75 cm) Preis & Verfügbarkeit

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Durapore 0,22 µm · Adaptercode 5 2-222 O-Ring mit ZentrierspitzeSortierung & Filter aufheben Show Filter
BestellnummerNominelle Filterelementlänge
CVGL51TP310 in. (25 cm) Preis & Verfügbarkeit
CVGL52TP320 in. (50 cm) Preis & Verfügbarkeit
CVGL53TP330 in. (75 cm) Preis & Verfügbarkeit

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Durapore 0,22 µm · Adaptercode 7 2-226 O-Ring, Bajonett mit ZentrierspitzeSortierung & Filter aufheben Show Filter
BestellnummerNominelle Filterelementlänge
CVGL75S015 in. (12.5 cm) Preis & Verfügbarkeit
CVGL71TP310 in. (25 cm) Preis & Verfügbarkeit
CVGL72TP320 in. (50 cm) Preis & Verfügbarkeit
CVGL73TP330 in. (75 cm) Preis & Verfügbarkeit

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Durapore 0,1 µm · Adaptercode 0, 2-222 O-RingSortierung & Filter aufheben Show Filter
BestellnummerNominelle Filterelementlänge
CVVL01TP310 in. (25 cm) Preis & Verfügbarkeit
CVVL02TP320 in. (50 cm) Preis & Verfügbarkeit
CVVL03TP330 in. (75 cm) Preis & Verfügbarkeit

Zurück nach oben

Durapore 0,1 µm · Adaptercode 5 2-222 O-Ring mit ZentrierspitzeSortierung & Filter aufheben Show Filter
BestellnummerNominelle Filterelementlänge
CVVL51TP310 in. (25 cm) Preis & Verfügbarkeit

Zurück nach oben

Durapore 0,1 µm · Adaptercode 7 2-226 O-Ring, Bajonett mit ZentrierspitzeSortierung & Filter aufheben Show Filter
BestellnummerNominelle Filterelementlänge
CVVL75S015 in. (12.5 cm) Preis & Verfügbarkeit
CVVL71TP310 in. (25 cm) Preis & Verfügbarkeit
CVVL72TP320 in. (50 cm) Preis & Verfügbarkeit
CVVL73TP330 in. (75 cm) Preis & Verfügbarkeit

Zurück nach oben

Documentation

Material Qualification Dossier

TitelVersion
6.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Literatur

Übersicht
Evaluation of Recovery Filters for Use in Bacterial Retention Testing of Sterilizing-Grade Filters
Carter, Jeff; Vol. 50, No.3 / May-June
Vol. 50, No.3 / May-June  1996

FAQ

FrageAntwort
Can Durapore 0.22 micron cartridges be used in the reverse direction?Durapore filters are bidirectionally supported. If the filter is inadvertently used in the reverse direction, a post-use integrity test will identify whether or not the filter cartridge was integral during processing. The specification for theis filter is > 50.0 psi for a water bubble point test and < 13.3 ml/minute per 10"element for a diffusion test. If the filter passes this test, no damage occured during use.

Please note that the maximum allowable pressure specification is different in the reverse direction - 50 psid vs. 80 psid in the forward direction.
What are the most common causes of filter clogging (air bubbles, particulates, surface tension, inappropriate filter size etc.)?Trapped bubbles, particulates and improper sizing are all common causes of fitration issues. True filter clogging is caused by particulates. Hard particles will form a cake on the filter surface. This will generally slow the filtration but not necessarily block filtration becuase fluid can flow through the layer of hard particles and then through the filter.

Deformable particles can compress across the filter pores, forming impermeable barriers to filtration. This type of problem is common with solutions containing proteins or lipids.
What is the compatibility of Durapore with high pH solutions?The upper recommended pH limit for Durapore membranes is 10. At pH >10, the hydrophilization layer of the membrane may become subject to hydrolysis. The extent of hydrolysis is a function of time, temperature , concentration and time of exposure. Upon exposure to high pH, the hydrophylization layer can swell which could result in a loss of permeability or flux. The hydrolysis of the hydrophilic layer will also lead to increased extractables from the membrane.
What are Millipore's general recommendations for filtering high pH solutions?For applications involving pH > 10, Millipore recommends the use or our PES membranes Express SHF or Express SHC. For information on these filters :

Express SHF: http://www.millipore.com/catalogue.nsf/docs/C8873
Express SHC: http://www.millipore.com/catalogue.nsf/docs/C9146
How can I differentiate filter plugging due to air bubbles, particulates, surface tension, inappropriate filter size, etc.?Air locking will occur when filtration is initiated without adequate venting or when air bubbles become trapped in fluid lines. Air will pass easily through a dry hydrophillic or hydrophobic filter. However, when a filter is wet and air is applied to a surface, the air will remain until it is manually moved upstream by venting or until the bubble point of the filter is reached. Bubble point is defined as the pressure at which gas displaces liquid for the largest set of filter pores and is able to flow through the pores. Air locking reduces the effective filtration area of the filter and thus reduces the flow rate.

Surface tension refers to the strong cohesive forces present between molecules at the surface of a liquid. The higher the surface tension, the more force is required to force fluid through the membrane..

Innapropriate filter size will can cause a filter to plug prematurely. Filter pore size is chosen based on the application. If the application requires a sterile fluid, than a 0.22 micron membrane would be used for standard solutions that have bacterial bioburden. A 0.1 micron filter would be used for applications where mycoplasma is a concern. Where virus contamination is a concern, ultrafiltration would be required. The selection of a filter pore size that is smaller than that required for the application will cause a decrease in filter capacity and an increase in cost.

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Kategorien

Biopharmaceutical Manufacturing > Downstream Processing > Sterile Filtration > Sterile Liquid > Durapore