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SCT070 BioTracker NIM-7 Lipids and Lysosomes Live Cell Dye

Live cell imaging fluorescent probe for simultaneous dual-color tracking of lipid droplets and lysosomes

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SCT070
1 mg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT070
      DescriptionBioTracker NIM-7 Lipids and Lysosomes Live Cell Dye
      OverviewLipid droplets (LDs) and lysosomes are specialized subunits within cells. LDs are the most hydrophobic sub-structures within cells and serve to store lipids for energy generation and membrane synthesis. Lysosomes are typically acidic organelles (pH 4.5–5.0) that play a critical role in the digestion and clearance of endocytosed and endogenous intracellular materials.

      BioTracker NIM-7 Lipids and Lysosomes Live Cell Dye is a naphthalimide-based fluorescent probe that allows lipid droplets and lysosomes to be labelled simultaneously and visualized separately using different excitation and detection channels. Lipid droplets and lysosomes can be visualized in the yellow and red fluorescence regions, respectively. The dye was found to have low cytotoxicity in multiple cell lines after 24 hour incubation. The dye also high photostability and can maintain 90% of original fluorescence intensity after 15 min of irradiation.

      Spectral properties:
      Lipid droplets: Excitation: 488 nm. Emission: 530-570 nm.
      Lysosomes: Excitation: 561 nm. Emission: 640-680 nm.

      References:
      Zheng X et al. Simultaneous dual-color tracking lipid droplets and lysosomes dynamics using a fluorescent probe. Chem. Sci. 2019, 10, 2342.
      Alternate Names
      • Live cell imaging probe
      • Lipid probe
      • Lysosomes probe
      References
      Product Information
      Detection methodFluorescence
      PresentationLyophilized
      Applications
      ApplicationLive cell imaging fluorescent probe for simultaneous dual-color tracking of lipid droplets and lysosomes
      Key Applications
      • Cell Based Assays
      Application NotesLive cell fluorescent imaging
      Biological Information
      Molecular Weight610.57
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancePurity: ≥ 98% confirmed by HPLC. Structure confirmed by HNMR, LC-MS and elemental analysis
      Molar Mass: 610.57 g/mol
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker NIM-7 Lipids and Lysosomes Live Cell Dye at -20°C, desiccate and protect from light
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT070 04061841441069